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- ArticleIakovlev NN, Aleksandrova GV, Batuner LS, Krasnova AF, Lenkova RI.Fiziol Zh SSSR Im I M Sechenova. 1978 Nov;64(11):1655-66.Biochemical and mathematical analysis revealed that metabolic processes in muscles, blood, liver, and brain during both unfatiguing muscular activity and in fatigue change their correlative bonds not identealby. The experiments exposed as a common traits, as differences in metabolic structure of both rapidly and slowly developed fatigue.